According to Facebook Ms Detlor is the social network's oldest user as well as the oldest person to visit Facebook's headquarters in Silicon Valley, California.
Ms Detlor was greeted by Facebook founder and CEO Mark Zuckerberg as well as Sheryl Sandberg, chief operating officer of Facebook during her tour of Facebook.
Mrs Sandberg later posted a photo to Facebook of herself with Ms Detlor and Mr Zuckerberg.
It was accompanied by the caption, "Honored to meet Florence Detlor, who at 101 years old is the oldest registered Facebook user. Thank you for visiting us Florence!”
Florence Detlor with Mark Zuckerberg and Sheryl Sandberg
According to her profile Ms Detlor graduated from Occidental College in Los Angeles in 1932. She lives in Menlo Park, California, coincidentally where Facebook now has its headquarters.
She joined Facebook in August 2009 and says that she is “looking for a good book to read.”
While Facebook has long been regarded as a tool for young people, there are now 955 million active Facebook users and the fastest growing demographic is women over the age of 55.
Several older people have been vying for Ms Detlor's title. Lily Strugnell from Cinderford, Gloucestershire, who turned 108 earlier this month, claimed that she was the oldest Facebook user in the world.
She also said that she was planning to open a Twitter account after taking a course for pensioners on how to use the internet.
In 2009 Ivy Bean became the oldest Tweeter after signing up for the micro-blogging site at the age of 104 from her residential home in the outskirts of Bradford.
At the time of her death in 2010 she had become an internet sensation, attracting more than 55,000 followers, including celebrities Chris Evans and Peter Andre.
She was invited to Downing Street to meet then Prime Minister Gordon Brown and tweeted that he was "really very nice", and his home was "beautiful inside".
