Which of the following cells produce hcl?
Parietal cells produce HCl by secreting hydrogen and chloride ions.
The correct answer is (D) Parietal Cell (Oxyntic Cells). Parietal Cells are large and are most numerous on the sidewalls of the gastric glands. These cells secrete hydrochloric acid and Castle's intrinsic factor.
Explanation: The stomach contains several cell types, each with a specific mechanism of action. Chief cells produce pepsinogen, which is converted to pepsin by hydrochloric acid in the stomach. Parietal cells produce hydrochloric acid, allowing this conversion.
The active components of gastric acid are protons and chloride. Often simplistically described as hydrochloric acid, these species are produced by parietal cells in the gastric glands in the stomach.
The cheif cells produce pepsinogen, which is the inactive pepsin enzyme and the parietal cells secrete HCl needed to activate pepsinogen.
The tight regulation of parietal cells ensures the proper secretion of HCl. The H+-K+-ATPase enzyme expressed in parietal cells regulates the exchange of cytoplasmic H+ for extracellular K+. The H+ secreted into the gastric lumen by the H+-K+-ATPase combines with luminal Cl− to form gastric acid, HCl.
Hydrochloric acid secretion by Parietal cells in stomach - YouTube
G-cells secrete gastrin into the systemic circulation, which allows the delivery of gastrin to parietal cells and enterochromaffin-like (ECL) cells in the gastric fundus and cardiac. Gastrin stimulates the proliferation of gastric mucosal endocrine cells (parietal cells, ECL cells).
The chief cells secrete pepsinogen, a moderately sized zymogen protein with a molecular weight of 40,400. Pepsin, an enzyme with a molecular weight of 32,700, is formed in the acidic environment of the stomach when pepsinogen loses its activation peptides.
How HCl is produced in the body?
In the human body, HCl is produced by the parietal cells of the stomach lining. The parietal cell cytoplasm combines with water and carbon dioxide to produce carbonic acid. The enzyme carbonic anhydrase converts one carbonic acid ion into a single hydrogen ion (H+) and a single bicarbonate ion (HCO3–).
Gastric juice is made up of digestive enzymes, hydrochloric acid and other substances that are important for absorbing nutrients – about 3 to 4 liters of gastric juice are produced per day. The hydrochloric acid in the gastric juice breaks down the food and the digestive enzymes split up the proteins.
Hydrochloric acid helps your body to break down, digest, and absorb nutrients such as protein. It also eliminates bacteria and viruses in the stomach, protecting your body from infection. Low levels of hydrochloric acid can have a profound impact on the body's ability to properly digest and absorb nutrients.
Which of the following cells in the gastric mucosa produce intrinsic factor and hydrochloric acid? Parietal cells are epithelial cells in the stomach that secrete HCl and intrinsic factor and located in the gastric glands found in the lining of the fundus and cardia regions of the stomach. 2.
Parietal cells secrete: Hydrochloric Acid: Serves to kill bacteria, activate enzymes, and to begin to breakdown chemical bonds of ingested food.
The antral mucosa secretes bicarbonate and contains mucus-secreting cells and G cells, which secrete gastrin, stimulating acid production.
Histamine stimulates parietal cells to secrete acid. 1.
Parietal cells are responsible for gastric acid secretion, which aids in the digestion of food, absorption of minerals, and control of harmful bacteria.
G-cells are neuroendocrine cells responsible for the synthesis and secretion of gastrin. They are primarily found in the pyloric antrum but can also be found in the duodenum and the pancreas.
The chief cells secrete pepsinogen, a moderately sized zymogen protein with a molecular weight of 40,400. Pepsin, an enzyme with a molecular weight of 32,700, is formed in the acidic environment of the stomach when pepsinogen loses its activation peptides.